When Infections are dominating
Each film coated tablet contains:
Cefixime 200mg, Ofloxacin 200mg
It is third generation oral cephalosporin,effective against a wide spectrum of sensitive gram positive, gram negative & anaerobic bacterial pathogens including beta-lactamase producing strains.It has high affinity for penicillin-binding proteins with varying site of activity. It acts by inhibition of bacterial cell-wall synthesis. The elimination half-life is about 3 hours, with little variation over the usual therapeutic dosage range.
Indication of CEFIXIME:
Infections of respiratory, urinary & biliary tract.
Hypersensitivity to penicillins. Severe renal impairment. Paediatrics:Safety upto 6 months age not established. Pregnancy: Use with caution. Lactation: Use with caution.
G-I disturbances. Headaches, dizziness. Rashes.
Salicylic acid & Probenecid.
Indications of OFLOXACIN:
Genito urinary, respiratory, Gastro-intestinal, Skin & Soft tissue infections. Peritonitis, Gonorrhoea.
Hypersensitivity to 4-quinolones. History of epilepsy.
Exposure to strong sun light and ultra violet rays should be avoided. Driving or operating machinery. Renal insufficiency, Psychiatric disorders concomitant use of aluminium and magnesium containing antacids. Paediatrics: Safety not established in children below 16 years. Pregnancy: Contraindicated. Lactation: Contraindicated. Elderly: Safe.
Hypersensitivity reactions,skin reactions, CNS disturbances,G.I upset pseudomembranous colitis.Transient increase in liver enzymes. Rarely, joint /muscle pain,bone marrow depression.
Antacids containing magnesium and aluminium reduce absorption. Sucralfate reduces absorption. Inhibits GABA receptor binding. Probenecid decreases elimination.
Pack (10×10 Tab)